Orexin receptor-1 mediates brown fat developmental differentiation
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چکیده
منابع مشابه
Orexin receptor-1 mediates brown fat developmental differentiation
Orexin A (OX) is a small excitatory neuropeptide hormone that stimulates feeding, wakefulness and energy expenditure via a pair of G-coupled protein receptors, namely orexin receptor-1 (OXR1) and orexin receptor-2 (OXR2). OX-deficient mice are sensitive to obesity despite being hypophagic. The obesogenic effect of OX-deletion is due to brown adipose tissue (BAT) dysfunction, a defect that origi...
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ژورنال
عنوان ژورنال: Adipocyte
سال: 2012
ISSN: 2162-3945,2162-397X
DOI: 10.4161/adip.18965